Eclipse BioInnovations is an RNA Next-Generation-Sequencing company founded in 2017 based on technology developed in Professor Gene Yeo’s laboratory at UC San Diego. The company´s mission is to use their first-in-class Eclipse-Seq RNA NGS platform technologies to accelerate the creation and development of truly safe and effective RNA medicines. Eclipse’s founders developed eCLIP-Seq, the world’s most efficient and unique CLIP-seq technology for identifying RNA binding protein gene partners and gene maps (van Nostrand et al. , Nature Methods 2016 and Nature 2020).

The portfolio of Eclipse BioInnovations comprises the following product lines:

• eCLIP-seq library preparation for RBP target sequencing
• m6A-eCLIP-seq for sequencing of m6A RNA methylation sites
• 5´and 3´ End-Seq for sequencing of transcription start and poly adenylation sites and transcript isomer detection
• FLI-seq for targeted sgRNA sequencing to optimize CRISPR Screen readouts

Eclipse BioInnovations´ technologies are also available as services, and can be customized for other RNAs such as miRNA or siRNA.

Find the latest publications powered by Eclipse BioInnovations technologies here