Cellular barcoding is a technique in which individual cells are labeled with unique nucleic acid sequences, termed barcodes, so that they can be monitored through space and time. This method can be used to track millions of cells in parallel, and thus is an efficient approach for investigating heterogeneous populations of cells. Over the past 25 years, cellular barcoding has been used for fate mapping, lineage tracing and high-throughput screening, and has led to important insights into developmental biology and gene function. The combination of cell barcode labeling with NGS has the potential to vastley increase our understanding of cell growth, differentiation, pathogenicity, and drug resistance.
Nucleus Biotech provides tools for analysis and discrimination of gene expression and phenotype variations in individual cells and cell sub-populations.