Neutralization and related viral binding/infection assays require cell lines with the appropriate receptors to make them susceptible to the virus. For coronaviruses, our partner Cellecta will engineer your cell line of interest to express the host receptor corresponding to the viral spike, such as the Ace2 receptor for SARS-CoV and Dpp2 for MERS-CoV.
Pseudoviruses are useful virological tools because of their safety and versatility, especially for emerging and re-emerging viruses.
Together with our partner Cellecta, we can offer custom lentiviral vectors packaged in viral particles pseudotyped with the particular viral protein of your interest (e.g. the coronavirus spike protein).