AsCpf1 (AsCas12a) (Acidaminococcus Cpf1/Cas12a) mRNA

Description

Ready-to-use synthetic AsCpf1 (AsCas12a) (Acidaminococcus Cpf1/Cas12a) mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes AsCpf1 (AsCas12a) (Acidaminococcus Cpf1/Cas12a) – designed for applications involving gene editing research and the development of CRISPR-Cas12a systems. AsCpf1 is a novel nuclease within the CRISPR-Cas family, offering high target specificity and low off-target effects, making it ideal for precise genome editing and functional genomics studies

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Tested for high purity, and characterized by low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized – also available in solution (1 mg/ml), please inquire

Shipping and Storage: Lyophilized mRNA shipped on gel packs. Store at –80°C upon arrival and after dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.