CancerMaster Panel, All-In-One-Kit (NGS Library Prep, Hyb Capture, Beads), for pre-capture pooling of 3 x 8 libraries

Description

Detect low-frequency variants incl. rearrangements, immuno-oncology signatures, as well as EBV and HPV in somatic cancer

• Targets 524 genes associated with somatic cancer and immunotherapy
• Target Size 2.5 Mb (Whole CDS incl. rearrangements for selected genes, selected regions of oncogenes, immune response genes, and EBV & HPV)
• Gene-Add-On Service when needed- contact us with your wish list
• Probes targeting mitochondrial or intronic/regulatory regions can also be spiked in – please inquire!
• Celemics´probe design ensures superior on-target performance, coverage, and uniformity
• Hard to capture sequences such as GC-rich, AT-rich and homologous sequences are equally represented
• Detection of SNV, Indel, CNV, MSI, TMB, EBV, HPV
• Full Bioinformatics Support available when needed
• Input: >50 ng fragmented DNA (FFPE, frozen tissue, RNA converted to cDNA)

Celemics´ CancerMaster Panel was developed to target all variant types involved in somatic tumor mutations, immuno-oncology markers, as well as Epstein-Barr virus (EBV) and Human Papillomaviruses (HPV) genes for cost-efficient and sensitive sequencing.

The All-In-One-Kit for pre-capture library pooling includes the NGS Library Kit developed for the Illumina Sequencing platform – user manual see here – and all accessories such as magnetic beads, Streptavidin beads, and Polymerase. For 64, 128, 384, and 768 samples kit sizes please contact us. All-In-One KIts for pre-capture library pooling for Ion Torrent and MGI platforms can also be ordered – please inquire!

The hyb capture panel – which is suitable for any sequencing platform including Illumina, Ion Torrent, MGI, PacBio and Oxford Nanopore – is also available without accessories and without library prep kit – please contact us us for pricing.