CD3 (CD3 epsilon gamma delta zeta complex) mRNA

Description

Ready-to-use CD3 (CD3 epsilon gamma delta zeta complex) mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes CD3 (CD3ε& CD3γ& CD3δ& CD3ζ). The CD3 complex is a key component of T cell receptor (TCR) signal transduction, consisting of four distinct subunits: CD3ε (epsilon), CD3γ (gamma), CD3δ (delta), and CD3ζ (zeta). Together, they form the TCR-CD3 signaling complex, which plays a critical role in T cell activation and immune response – for research and development in the context of immune cell reprogramming (e.g., CAR-T, TCR-T) or in vitro T cell function studies, offering advantages of high expression efficiency and stable translation

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Tested for high purity, low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized          – also available in solution (1 mg/ml), please inquire

Shipping and Storage:   Lyophilized mRNA shipped at room temperature (≤ 25°C). Store at –80°C upon dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.