CD38 mRNA

Description

Ready-to-use CD38 mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes CD38, a transmembrane glycoprotein and ADP ribosyl cyclase broadly expressed on B cells, plasma cells, T cells, NK cells,
and myeloid cells. It plays a crucial role in cell adhesion, signal transduction, and metabolic regulation. CD38 is highly expressed in
hematologic malignancies such as multiple myeloma (MM) and chronic lymphocytic leukemia (CLL), making it an important target for CAR-T cell immunotherapy and anti-CD38 monoclonal antibody treatments (e.g., Daratumumab) – for research and development in plasma cell immunology research, CAR-T and immunotherapy studies, mRNA delivery research, and multiple myeloma (MM) investigations

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Tested for high purity, low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized          – also available in solution (1 mg/ml), please inquire

Shipping and Storage:   Lyophilized mRNA shipped at room temperature (≤ 25°C). Store at –80°C upon dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.