CD48 mRNA

Description

Ready-to-use CD48 mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes CD48,  a member of the immunoglobulin superfamily (IgSF),  broadly expressed on activated T cells, NK cells, B cells, dendritic cells, and monocytes. It plays a critical role in immune cell interactions, signal transduction, and immune responses. As a ligand for the 2B4 (CD244) receptor, CD48 is essential for NK cell and T cell immune regulation – for research and development in T cell activation mechanisms, NK cell immunology studies, mRNA delivery research, tumor immune regulation research, studies related to infection, inflammation, and the tumor
microenvironment.

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Tested for high purity, characterized by low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized          – also available in solution (1 mg/ml), please inquire

Shipping and Storage:   Lyophilized mRNA shipped on gel packs. Store at –80°C upon arrival and after dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.