The CleanPlex® Familial Hypercholesterolemia NGS Panel for Illumina® or Ion Torrent™ is a multiplex PCR-based targeted sequencing assay designed to simplify the evaluation of germline variants across the 4 genes (APOB, LDLR, LDLRAP1, PCSK9) related to Familial Hypercholesterolemia. The panel targets all exonic regions of those 4 genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The panel is optimized to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.
The CleanPlex Familial Hypercholesterolemia Panel contains CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.
You have the option to modify the existing content of this pre-designed panel. Please contact us for a quote.