CXCR4 mRNA

Description

Ready-to-use CXCR4 mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes PC-X-C chemokine receptor type 4 (CXCR4), a receptor for CXCL12 (SDF-1) critical for hematopoietic stem cell homing. This synthetic mRNA enables controlled expression of CXCR4 for research in stem cell mobilization, HIV entry mechanisms, and tumor metastasis where CXCR4 signaling promotes cell migration and survival.

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Levostar catalog mRNAs are tested for high purity, and are characterized by low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized  – also available in solution (1 mg/ml), please inquire

Shipping and Storage: Lyophilized mRNA shipped on gel packs. Store at –80°C upon arrival and after dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.