FLTL3 mRNA

Description

Ready-to-use FLTL3 mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes Fms-like Tyrosine Kinase 3 Ligand, FLT3 Ligand (FLT3L). It is suitable for research on dendritic cell (DC) expansion, hematopoietic stem cell biology, and cancer immunotherapy. FLT3L is a hematopoietic growth factor that plays a key role in the proliferation of dendritic cells and the maintenance of hematopoietic stem cells. It is widely used in cancer immunotherapy and
the development of DC-based vaccines

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Tested for high purity, low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized          – also available in solution (1 mg/ml), please inquire

Shipping and Storage:   Lyophilized mRNA shipped at room temperature (≤ 25°C). Store at –80°C upon dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.