IL5 (IL-5) mRNA

Description

Ready-to-use IL5 (IL-5) mRNA

For in vitro mRNA transfection and in vivo mRNA delivery by injection

Encodes IL5 (Interleukin-5), IL-5, a key cytokine involved in the regulation of eosinophil proliferation and activation. IL-5 plays an important role in asthma and eosinophil-related disorders and serves as a critical target for therapeutic monoclonal antibodies such as Mepolizumab – for research and development in the context of eosinophil function and allergic diseases

Manufactured by Levostar´s monoPlasmid technology

Designed for optimal expression results:

• Enhanced polyA(+) Stability – for preventing RNA degradation

• Cap1 Structure – for optimal ribosome recruiting

• Carefully selected UTR Regions – to enhance translation initiation

N1-Methylpseudouridine Modification

For enhanced mRNA stability and decreased anti-mRNA immune response Levostar´s catalog mRNAs are in vitro transcribed using N1-Methylpseudouridine (N1-Me-Ψ, N1mpU) by default. If you prefer unmodified mRNA or you require a different modification, please contact us.

Quality Standards: Levostar catalog mRNAs are tested for high purity, and are characterized by low endotoxin,  low residual dsRNA & plasmid template DNA, high capping efficiency, and proper polyA(+)-length.

Contents:  1 mg mRNA, lyophilized   – also available in solution (1 mg/ml), please inquire

Shipping and Storage: Lyophilized mRNA shipped on gel packs. Store at –80°C upon arrival and after dissolving.

For other mRNA quantities than 1 mg including bulk offers please contact us for pricing

mRNA may also be ordered already encapsulated in Lipid Nanoparticles for high efficiency mRNA delivery – please contact us for a quotation.

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.