Jurkat T-Cell Receptor (TCR) Control (CMV) Reporter Cell Line (NFAT-GFP)

Description

Jurkat CMV TCR NFAT-GFP CD8 Reporter Cells, Control

30% introductory discount until December 31, 2025

• Polyclonal derivative of the Jurkat E6.1 Line, Bleo and Puro resistant
• Express CD8 (important to stabilize TCR-MHC interaction by increased TCR-R-pMHC affinity and boosting TCR signaling)
• Stably express HLA-A 02:01 restricted CMV antigen-specific T-Cell Receptor

The control Jurkat CMV TCR reporter selected cell pool was engineered by introducing the HLA-A 02:01 restricted CMV-TCR in the Jurkat TCR K/O NFAT-GFP Reporter Cell Line using puromycin selection.

Applications:

This cell line can be used as a positive control in target peptide/mini gene testing or screening, e.g. by co-culturing with K562 CMV Epitope expressing HLA-A02:01 Antigen-Presenting Cells (APCs), Control, (RFP)