LNP Encapsulation Service

Description

Customized LNP Encapsulation

For in vitro RNA transfection and in vivo RNA delivery by injection

Nucleus Biotech presents Levostar´s NeoLNP encapsulation services – now you can obtain high quality LNPs tailored to your needs at unmatched turn-around time and cost efficiency.

Designed for optimal RNA delivery results:

• Suitable for transfecting mRNA, siRNA, circRNA, saRNA, and other types of RNA

• Fully integrated technology platform covering gene synthesis, plasmid preparation, mRNA-, circRNA- or saRNA- synthesis (or premade mRNA, circRNA, saRNA), and LNP encapsulation

• Antibody-conjugated LNPs for improved targeting and transfection efficiencies

• Flexible Scaling Capacity: Manufacturing from 1 mg to 100 mg

• Superior Nanoparticle Characterization: QC analytics ensures precision and reliability

Encapsulation Service Details

RNA Length:  100 nt – 20000 nt (mRNA)

RNA Quantity: 1 mg – 100 mg

RNA Content:  0.3±0.03 mg/ml

Cationic Lipids: SM102  or   ALC-0315

pH: 6.0 – 8.0

Size Distribution: 40-180 nm

PDI: ≤ 0.5

Encapsulation Efficiency: ≥ 85%

Delivery: In aliquots per dry ice shipment

Optional Test Annotation：Zeta, Empty Vesicle Ratio

Contact us for a quotation – or specify your needs and send them to info@nucleusbiotech.com

For mRNA encapsulation in your lab and subsequent in vitro mRNA transfection or in vivo mRNA delivery we offer Levostar´s portfolio of NeoLNP Kits.