Capture 190 kb human MHC core region from genome wide libraries for targeted sequencing
• Covers exons, introns, 5’ regulatory regions, 3’ regulatory regions, and beyond
• Detection of SNPs, indels, and structural variants/CNVs
• Save sequencing costs by selectively capturing the human MHC Core Region
BioDynami´s MHC Core Region Capture Kit enables the most cost-effective targeted sequencing of 190 kb of the human MHC Core region comprising 22 MHC genes, including all coding and non-coding regions. The MHC Core Region Capture Kit was developed to capture the MHC Core region from whole genome NGS libraries based on the CATCH-Seq technology. Comprehensive sequencing of the entire region makes it possible to detect SNPs, indels, and structural variants/CNVs that are not covered by other MHC targeted sequencing reagents. You may also apply the captured DNA to Bisulfite-Sequencing for analyzing methylation patterns.