Description
Prepare NGS DNA Library and capture full 3.8 MB human MHC region for targeted sequencing
• Integration of NGS library prep and MHC capture simplifies the procedure and enhances the capture efficiency
• Covers exons, introns, 5’ regulatory regions, 3’ regulatory regions, and beyond
• Detection of SNPs, indels, and structural variants/CNVs
• Save sequencing costs by selectively capturing the human MHC Region
• Index Primers for sample multiplexing included
BioDynami´s MHC Library Prep and Capture Kit enables the most cost-effective targeted sequencing of 3.8 Mb of the human MHC locus, including all coding and non-coding regions. The MHC Library Prep & Capture Kit was developed to combine NGS library prep and MHC locus capture based on the CATCH-Seq technology. The integration of library prep and MHC capture not only simplifies the procedure, but also enhances the capture efficiency. Comprehensive sequencing of the entire locus enables detection of SNPs, indels, and structural variants/CNVs that are not covered by other MHC targeted sequencing reagents..
Sample multiplexing is offered as follows:
• Multiplexing Index Primers: For kit with 24 reactions (Cat. # 30012S)
• Multiplexing Unique Dual Index Primers: For kit with 96 reactions (Cat. # 30012L)