Package any third-generation lentviral vector as SARS-CoV spike protein (S-protein) pseudotyped lentiviral particles that can be used to run coronavirus neutralization assays and similar infection studies under S2 guidelines. The SARS Spike Protein Pseudotyped Lentiviral Packaging Mix uses the same packaging system as Cellecta’s standard VSV-G Packaging Mix, but substitutes the gene for the viral coat protein with the SARS coronavirus S-protein.
The provided amount of packaging plasmid mix is sufficient for ~12 x 10-cm2 plates to produce 1-2 x 10e7 TU.
Packaging systems for wildytpe SARS-CoV and SARS-CoV-2 spike proteins as well as for the SARS-CoV-2 S D614 mutation and the spike proteins of all SARS-COV-2 emerging variants are available – for an overview click here. We can also supply lentiviral Luciferase and GFP reporter constructs for producing pseudotyped lentiviral particles as described here – please contact us for a quotation.