Welcome to Nucleus Biotech – Core Reagents & Services for Life Science Research

Focus on Functional Genomics for Target Gene and Biomarker Discovery

Nucleus Biotech GmbH provides enabling reagents and services to life science researchers in academia and industry. Cutting edge methods, competent advice and in-depth knowledge of customer requirements, both in day-to-day laboratory work and for particularly challenging issues, are the company’s main strengths.

Nucleus Biotech sources partner companies that develop and market the latest technologies to make them available to you, our valuable customers. Cellecta (Mountain View, California, USA) are our resource of lentiviral sgRNA-, shRNA-, and barcode-libraries for CRISPR- and RNAi-based target screening and cellular barcoding. Readouts are performed by Next Generation Sequencing (NGS) available in kit format or as customized service. Further highly innovative NGS-based methods in the portfolio are Hi-C Sequencing for 3-dimensional genome studies, TELL-Seq for long range sequencing on short read sequencers by linked-reads, and in the biomarker discovery arena TCR/BCR-Seq for Adaptive Immune Receptor Profiling as well as BioLiqX Small RNA-Seq for analysis of picogram amounts of cell-free RNA in liquid biopsy samples – developed by our local partner Heidelberg Biolabs. Complemented by appropriate high-purity exosome purification kits from Nexotech (Lugo, Galicia, Spain).

Nucleus Biotech GmbH is based in Heidelberg/Germany, one of the hot spots for life science research in Germany. The company addresses customers throughout Europe, for some distribution lines restricted to Germany, Austria, and Switzerland.