RNA-Seq Barcode Pooled Libraries

RNA-Seq Barcode Pooled Libraries link genetic barcode labeling of cells  with changes in expression profiles. The approach provides a convenient way to identify cell variations with unique characteristics or biology, and to understand how these groups of variant cells evolve in response to drug treatment, tumor metastasis, or other conditions.
Nucleus Biotech offers CloneTracker XP Barcode Libraries, where the barcode is positioned in the 3’-UTR (or 5′-UTR) of the selection marker so it is expressed as part of the RNA transcript in the cells. As a result, it can be detected by RNA sequencing, as well as DNA sequencing.


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