Maintaining RNA stability and protecting it from degradation is a significant challenge. Current RNA stabilization methods such as PAXgene, Tempus, RNAgard or dry blood spots all require invasive blood collection resulting in low compliance because of very limited shelf life which requires immediate sample processing and the need to invest in cold storage infrastructure.
Non-invasive RNA collection traditionally suffers from low quality RNA as well as short shelf life storage.
MAWI´s iSWAB-RNA device is the solution:
It allows for the non-invasive collection, concentration, and stabilization of intact buccal cells and/or any mammalian cells collected with a swab or cytobrush and real time ambient stabilization of Total RNA from the point of collection to processing.
The unique and patented design of Mawi’s iSWAB-RNA tubes enables mechanistic release of cells into a proprietary lysis and stabilization buffer, resulting in the recovery of nearly all cells from single or several swabs. iSWAB™ tubes are designed to facilitate collection, sample concentration, transport, extraction, and long term storage at room temperature, all in a single tube. The tubes are suitable for either manual or automated RNA preparation.