SARS-CoV-2 Host Cell Entry Factor Expression Constructs

ACE2, TMPRSS2, CD147, and NRP1  are the main entry factors in human host cells for SARS-COV-2.  GenTarget´s lentiviral particles enable you to over-express these proteins in any cell type, including primary cells. You can study SARS-CoV-2-host cell interactions and screen for potential virus entry inhibitors.

The lentiviral particles can be used for regular constitutive high expression (without any induction) or for inducible expression with tetracycline or Dox induction when the tetracycline repressor protein (TetR) is present.

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