CleanPlex TP53 NGS Panel

Description

The CleanPlex® TP53 NGS Panel for Illumina® or Ion Torrent™ is a multiplex PCR-based targeted sequencing assay designed to simplify the evaluation of somatic and germline variants across the TP53 gene

• Sensitive Detection – Detect somatic mutations as low as 1% variant allele frequency using just 20 ng of DNA
• Fast, Streamlined Workflow – Generate sequencing-ready libraries for Illumina or Ion Torrent platforms in just 3 hours using a rapid, three-step protocol
• Superb Performance – Prepare high-quality NGS libraries with excellent on-target performance using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs

The CleanPlex® TP53 Multiplex PCR-based NGS Panel – designed to simplify the evaluation of somatic and germline variants across the TP53 gene – targets all exonic regions and flanking intronic sequences of TP53. Starting with just 20 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The panel is optimized to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

Kit Contents: Multiplex PCR Primers and PCR Reagents, & CleanPlex Targeted NGS Library Preparation Kit with CleanPlex purification reagents

Additional Products which can be ordered separately:
CleanMag® Magnetic Beads – for library purification and size selection
CleanPlex® Dual-Indexed PCR Primers – for multiplexing up to 192 samples per sequencing run
CleanPlex® Single-Indexed PCR Primers for Ion Torrent