PharmacoScreen Anti Tuberculosis Panel, All-In-One-Kit (NGS Library Prep, Hyb Capture, Beads), for pre-capture pooling of 3 x 8 libraries
1.943,00 €
Description
Pharmacogenomics NGS Panel to assess genes involved in drug-induced liver injury
• Targets 132 genes associated with drug-induced liver injury (e.g. by anti tuberculosis drugs)
• Target Size 186 kb (Whole CDS, UTR -50 bp, +10 bp)
• Gene-Add-On Service when needed- contact us with your wish list
• Probes targeting mitochondrial or intronic/regulatory regions can also be spiked in – please inquire!
• Celemics´probe design ensures superior on-target performance, coverage, and uniformity
• Hard to capture sequences such as GC-rich, AT-rich and homologous sequences are equally represented
• Detection of SNV, Indel, CNV
• Full Bioinformatics Support available when needed
• Input: >50 ng fragmented DNA (blood)
The PharmacoScreen Anti-tuberculosis Panel assesses genes associated with liver injury. Drug-induced liver injury (DILI), which is an important cause of acute liver failure, can be a threat to a patient and a common reason why some drug development projects are discontinued. Anti-tuberculosis drugs are reported to be the most common factor that leads to DILI demanding precise and personalized medicine based on the patient´s genetic background.
The All-In-One-Kit for pre-capture library pooling includes the NGS Library Kit developed for the Illumina Sequencing platform – user manual see here – and all accessories such as magnetic beads, Streptavidin beads, and Polymerase. For 64, 128, 384, and 768 samples kit sizes please contact us. All-In-One KIts for pre-capture library pooling for Ion Torrent and MGI platforms can also be ordered – please inquire!
The hyb capture panel – which is suitable for any sequencing platform including Illumina, Ion Torrent, MGI, PacBio and Oxford Nanopore – is also available without accessories and without library prep kit – please contact us us for pricing.
