PharmacoScreen Epilepsy Panel, All-In-One-Kit (NGS Library Prep, Hyb Capture, Beads)
3.260,00 €
Description
Pharmacogenomics NGS Panel to assess genes involved in the metabolism of anti-epileptic drugs
• Targets 91 genes associated with anti-epileptic drugs
• Target Size 575 kb (Whole CDS, UTR -50 bp, +10 bp)
• Gene-Add-On Service when needed- contact us with your wish list
• Probes targeting mitochondrial or intronic/regulatory regions can also be spiked in – please inquire!
• Celemics´probe design ensures superior on-target performance, coverage, and uniformity
• Hard to capture sequences such as GC-rich, AT-rich and homologous sequences are equally represented
• Detection of SNV, Indel, CNV
• Full Bioinformatics Support available when needed
• Input: >50 ng fragmented DNA (blood)
The PharmacoScreen Epilepsy Panel, designed for research studies on epilepsy, consists of 91 genes associated with anti-epileptic drugs. Epilepsy is one of the most common neurological disorders, with an estimated prevalence of one out of 100 worldwide and constantly increasing. Epilepsy is usually treated by consistent application of anti-epileptic drugs. The aim of the treatment is to prevent seizures with no issues of side effects. Although over 20 different anti-epileptic drugs have been developed, most of the drugs failed to prevent seizures, or faced challenges of determining the proper dosage for an individual patient. The genetic background is one of the most important clinical factors to be considered.
The All-In-One-Kit includes the NGS Library Kit developed for the Illumina Sequencing platform – user manual see here – and all accessories such as magnetic beads, Streptavidin beads, and Polymerase. For 48 rxns and 96 rxns kit sizes please contact us. All-In-One KIts for Ion Torrent and MGI platforms can also be ordered – please inquire!
The hyb capture panel – which is suitable for any sequencing platform including Illumina, Ion Torrent, MGI, PacBio and Oxford Nanopore – is also available without accessories and without library prep kit – please contact us us for pricing.
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